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CsV03-3 is a member of a novel gene family from citrus that encodes a protein with DNA binding activity and whose expression is responsive to defense signals and abiotic stress. J Plant Physiol (2008) 165: 531-543 |
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Isolation and characterization of carnocyclin a, a novel circular bacteriocin produced by Carnobacterium maltaromaticum UAL307. Appl. Environ. Microbiol. (2008) 74: 4756-4763 |
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Colgrave ML, Kotze AC, Ireland DC, Wang CK, Craik DJ
The anthelmintic activity of the cyclotides: natural variants with enhanced activity Chembiochem (2008) 9: 1939-1945 |
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Cyclotides: natural, circular plant peptides that possess significant activity against gastrointestinal nematode parasites of sheep. Biochemistry (2008) 47: 5581-5589 |
Cemazar M, Joshi A, Daly NL, Mark AE, Craik DJ
The structure of a two-disulfide intermediate assists in elucidating the oxidative folding pathway of a cyclic cystine knot protein. Structure (2008) 16: 842-851 |
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Structural Basis of Transcription Inhibition by Alpha-Amanitin and Implications for RNA Polymerase II Translocation. Nat Struct Mol Biol (2008) 15: 811-818 |
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Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae Proc Natl Acad Sci U S A (2008) 105: 1221-1225 |
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Identification of two suites of cyclotide precursor genes from metallophyte Viola baoshanensis: cDNA sequence variation, alternative RNA splicing and potential cyclotide diversity Gene (2009) 431: 23-32 |
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Combined X-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold. J Biol Chem (2009) 284: 10672-10683 |
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Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes. Biophys J. (2009) 97: 1471-1481 |
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Circular proteins from Melicytus (Violaceae) refine the conserved protein and gene architecture of cyclotides. Org Biomol Chem (2009) 7: 2378-2388 |
Sawa N, Zendo T, Kiyofuji J, Fujita K, Himeno K, Nakayama J, Sonomoto K
Identification and characterization of lactocyclicin Q, a novel cyclic bacteriocin produced by Lactococcus sp. strain QU 12. Appl Environ Microbiol (2009) 75: 1552-1558 |
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The three-dimensional structure of carnocyclin A reveals that many circular bacteriocins share a common structural motif. J. Biol. Chem. (2009) 284: 28674-28681 |
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The conserved glu in the cyclotide cycloviolacin O2 has a key structural role. Chembiochem (2009) 10: 2354-2360 |
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Isolation and Characterization of Bioactive Cyclotides from Viola labridorica Helvetica Chimica Acta (2010) 93: 2287-2295 |
Tang J, Wang CK, Pan X, Yan H, Zeng G, Xu W, He W, Daly NL, Craik DJ, Tan N
Isolation and characterization of cytotoxic cyclotides from Viola tricolor. Peptides (2010) 31: 1434-1440 |
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De novo sequencing of two new cyclic theta-defensins from baboon (Papio hamadryas) leukocytes by matrix-assisted laser desorption/ionization mass spectrometry. Rapid Commun Mass Spectrom (2010) 24: 599-604 |
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Identification of candidates for cyclotide biosynthesis and cyclisation by expressed sequence tag analysis of Oldenlandia affinis. BMC Genomics (2010) 11: 111-0 |
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Backbone dynamics of cyclotide MCoTI-I free and complexed with trypsin. Angew. Chem. Int. Ed. Engl. (2010) 49: 7030-7034 |
Plan MR, Rosengren KJ, Sando L, Daly NL, Craik DJ
Structural and biochemical characteristics of the cyclotide Kalata B5 from Oldenlandia affinis. Biopolymers (2010) 94: 647-658 |
Mylne JS, Wang CK, van der Weerden NL, Craik DJ
Cyclotides are a component of the innate defense of Oldenlandia affinis. Biopolymers (2010) 94: 635-646 |
Gerlach SL, Rathinakumar R, Chakravarty G, Göransson U, Wimley WC, Darwin SP, Mondal D
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Isolation, characterization, and bioactivity of cyclotides from the Micronesian plant Psychotria leptothyrsa J Nat Prod (2010) 73: 1207-1213 |
Daly NL, Chen B, Nguyencong P, Craik DJ
Structure and Activity of the Leaf-Specific Cyclotide vhl-2. Australian Journal of Chemistry (2010) 63: 771-778 |
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A new ‘era’ for cyclotide sequencing. Biopolymers: Peptide Science (2010) 94: 592-601 |
Burman R, Gruber CW, Rizzardi K, Herrmann A, Craik DJ, Gupta MP, Göransson U
Cyclotide proteins and precursors from the genus Gloeospermum: filling a blank spot in the cyclotide map of Violaceae. Phytochemistry (2010) 71: 13-20 |
Breuillin,F., Schramm,J., Hajirezaei,M., Ahkami,A., Favre,P., Druege,U., Hause,B., Bucher,M., Kretzschmar,T., Bossolini,E., Kuhlemeier,C., Martinoia,E., Franken,P., Scholz,U. and Reinhardt,D.
Phosphate systemically inhibits development of arbuscular mycorrhiza in Petunia hybrida and represses genes involved in mycorrhizal functioning. Plant J. (2010) 64: 1002-1017 |
Zenoni,S., D Agostino,N., Tornielli,G.B., Quattrocchio,F., Chiusano,M.L., Koes,R., Zethof,J., Guzzo,F., Delledonne,M., Frusciante,L., Gerats,T. and Pezzotti,M.
Revealing impaired pathways in the an11 mutant by high-throughput characterization of Petunia axillaris and Petunia inflata transcriptomes. Plant J. (2011) 68: 11-27 |
Yuan,C., Chen,L., Meehan,E.J., Daly,N., Craik,D.J., Huang,M. and Ngo,J.C.
Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1. BMC Struct. Biol. (2011) 11: 30-0 |
Yeshak MY, Burman R, Asres K, Göransson U
Cyclotides from an Extreme Habitat: Characterization of Cyclic Peptides from Viola abyssinica of the Ethiopian Highlands J Nat Prod (2011) [ahead]: 0-0 |
Wong CT, Taichi M, Nishio H, Nishiuchi Y, Tam JP
Optimal Oxidative Folding of the Novel Antimicrobial Cyclotide from Hedyotis biflora Requires High Alcohol Concentrations. Biochemistry (2011) [ahead]: 0-0 |
Wang,C.K., Clark,R.J., Harvey,P.J., Rosengren,K.J., Cemazar,M. and Craik,D.J.
The role of conserved Glu residue on cyclotide stability and activity: a structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant. Biochemistry (2011) 50: 4077-4086 |
Sando,L., Henriques,S.T., Foley,F., Simonsen,S.M., Daly,N.L., Hall,K.N., Gustafson,K.R., Aguilar,M.I. and Craik,D.J.
A Synthetic mirror image of kalata B1 reveals that cyclotide activity is independent of a protein receptor. Chembiochem (2011) 12: 2456-2462 |
Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ
Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins. ACS Chem Biol (2011) 6: 345-355 |
Poth AG, Colgrave ML, Lyons RE, Daly NL, Craik DJ
Discovery of an unusual biosynthetic origin for circular proteins in legumes Proc Natl Acad Sci USA (2011) 108: 10127-10132 |
Ovesen,R.G., Nielsen,J. and Hansen,H.C.
Biomedicine in the environment: sorption of the cyclotide kalata B2 to montmorillonite, goethite, and humic acid. Environ. Toxicol. Chem. (2011) 30: 1785-1792 |
Nguyen,G.K., Zhang,S., Wang,W., Wong,C.T., Nguyen,N.T. and Tam,J.P.
Discovery of a linear cyclotide from the bracelet subfamily and its disulfide mapping by top-down mass spectrometry. J. Biol. Chem. (2011) 286: 44833-44844 |
Nguyen,G.K., Zhang,S., Nguyen,N.T., Nguyen,P.Q., Chiu,M.S., Hardjojo,A. and Tam,J.P.
Discovery and characterization of novel cyclotides originated from chimeric precursors consisting of albumin-1 chain a and cyclotide domains in the Fabaceae family. J. Biol. Chem. (2011) 286: 24275-24287 |
Mylne JS, Colgrave ML, Daly NL, Chanson AH, Elliott AG, McCallum EJ, Jones A, Craik DJ.
Albumins and their processing machinery are hijacked for cyclic peptides in sunflower. Nat Chem Biol (2011) 7: 257-259 |
Masuda,Y., Ono,H., Kitagawa,H., Ito,H., Mu,F., Sawa,N., Zendo,T. and Sonomoto,K.
Identification and characterization of leucocyclicin Q, a novel cyclic bacteriocin produced by Leuconostoc mesenteroides TK41401. Appl. Environ. Microbiol. (2011) 77: 8164-8170 |
He,W., Chan,L.Y., Zeng,G., Daly,N.L., Craik,D.J. and Tan,N.
Isolation and characterization of cytotoxic cyclotides from Viola philippica. Peptides (2011) 32: 1719-1723 |
Hashempour,H., Ghassempour,A., Daly,N.L., Spengler,B. and Römpp,A.
Analysis of cyclotides in Viola ignobilis by Nano liquid chromatography fourier transform mass spectrometry. Protein Pept. Lett. (2011) 18: 747-752 |
Contreras,J., Elnagar,A.Y., Hamm-Alvarez,S.F. and Camarero,J.A.
Cellular uptake of cyclotide MCoTI-I follows multiple endocytic pathways. J Control Release (2011) 155: 134-143 |
Condie JA, Nowak G, Reed DW, Balsevich JJ, Reaney MJ, Arnison PG, Covello PS
The biosynthesis of Caryophyllaceae-like cyclic peptides in Saponaria vaccaria L. from DNA-encoded precursors. Plant J (2011) 67: 682-90 |
Chan,L.Y., Gunasekera,S., Henriques,S.T., Worth,N.F., Le,S.J., Clark,R.J., Campbell,J.H., Craik,D.J. and Daly,N.L.
Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds. Blood (2011) 118: 6709-6717 |
Cascales,L., Henriques,S.T., Kerr,M.C., Huang,Y.H., Sweet,M.J., Daly,N.L. and Craik,D.J.
Identification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptides. J. Biol. Chem. (2011) 286: 36932-36943 |
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Cyclotide-membrane interactions: defining factors of membrane binding, depletion and disruption. Biochim. Biophys. Acta (2011) 1808: 2665-2673 |
Borrero J, Brede DA, Skaugen M, Diep DB, Herranz C, Nes IF, Cintas LM, Hernández PE
Characterization of garvicin ML, a novel circular bacteriocin produced by Lactococcus garvieae DCC43, isolated from mallard ducks (Anas platyrhynchos). Appl Environ Microbiol (2011) 77: 369-373 |
Wong,C.T., Rowlands,D.K., Wong,C.H., Lo,T.W., Nguyen,G.K., Li,H.Y. and Tam,J.P.
Orally active peptidic bradykinin B1 receptor antagonists engineered from a cyclotide scaffold for inflammatory pain treatment. Angew. Chem. Int. Ed. Engl. (2012) 51: 5620-5624 |
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Braces for the peptide backbone: insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations. Angew. Chem. Int. Ed. Engl. (2012) 51: 3708-3712 |
Poth,A.G., Mylne,J.S., Grassl,J., Lyons,R.E., Millar,A.H., Colgrave,M.L. and Craik,D.J.
Cyclotides associate with leaf vasculature and are the products of a novel precursor in petunia (Solanaceae). J. Biol. Chem. (2012) 287: 27033-27046 |
Pinto,M.F., Fensterseifer,I.C., Migliolo,L., Sousa,D.A., de Capdville,G., Arboleda-Valencia,J.W., Colgrave,M.L., Craik,D.J., Magalhães,B.S., Dias,S.C. and Franco,O.L.
Identification and structural characterization of novel cyclotide with activity against an insect pest of sugar cane. J. Biol. Chem. (2012) 287: 134-147 |
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Novel cyclotides and uncyclotides with highly shortened precursors from Chassalia chartacea and effects of methionine oxidation on bioactivities. J. Biol. Chem. (2012) 287: 17598-17607 |
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Cyclic peptides arising by evolutionary parallelism via asparaginyl-endopeptidase-mediated biosynthesis. Plant Cell (2012) 24: 2765-2778 |
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Design, synthesis, structural and functional characterization of novel melanocortin agonists based on the cyclotide kalata B1. J. Biol. Chem. (2012) 287: 40493-40501 |
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