MCo-CVX-6D(1213) Protein Card

General Information
Name MCo-CVX-6D
Sequence VCPK(DOTA)ILQRCRRDSDCPGACICRGNGYCGSYRJCR
GpRRBCYJR
Class Squash trypsin inhibitor
Average Mass NA
Monoisotopic Mass 0
m/z M+H 0
ProteinType Wild type
Parent
Organism Synthetic
Notes Representative curves of in vitro inhibition of CXCL12-Red binding to CXCR4 by MCo-CVX-6D demonstrating that conjugation with DOTA to produce MCo-CVX-6D does not affect their affinity towards CXCR4.
Cyclic Yes

Assay
No assays found

References
Lesniak, W.G., Aboye, T., Chatterjee, S., Camarero, J.A. and Nimmagadda, S. (2017) In vivo evaluation of an engineered cyclotide as specific CXCR4 imaging reagent Chemistry‚ÄďA European Journal 23:14469-14475

Cross-references
Nucleic acids
Structure
Links

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